Coproverdine, a novel, cytotoxic marine alkaloid from a new zealand ascidian.

نویسندگان

  • Sylvia Urban
  • John W Blunt
  • Murray H G Munro
چکیده

The crude extract of a New Zealand ascidian displayed antitumor activity. Bioassay-directed fractionation yielded a novel alkaloid, coproverdine (1). The structure of 1 was assigned on the basis of detailed spectroscopic analysis. Coproverdine (1) was responsible for the antitumor activity of the crude extract.

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عنوان ژورنال:
  • Journal of natural products

دوره 65 9  شماره 

صفحات  -

تاریخ انتشار 2002